The monograph presents the results obtained by research group of authors from Republic of Moldova, Ukraine, Czech Republic, Poland and Slovakia. Research work is an interesting scientific and practical study of the problems of innovative development of the economy at the present stage. The content of each section of the monograph corresponds to the general conceptual logic of the work. The international collective monograph consists of three sections: 1. Theoretical and methodological foundations of enterprises’ transition to innovative development. 2. Strategies for innovative development of regional socioeconomic systems. 3. Digitalization as the basis for innovative development of economics processes These results illustrate the need to development mechanisms of innovative development of the countries and regions, which stimulate the acceleration of information and knowledge exchange between all stakeholders. Monograph is interesting and useful for experts engaged in research in the field of economics both at the micro-level of the enterprise, and at the meso- and macro-levels — regional and national. Presented studies is interesting for specialists in the field of innovative development and can be recommended for use by doctoral students, masters and students of higher educational institutions, practitioners and employees of local public administration authorities.